Get Antibacterial Agents: Chemistry, Mode of Action, Mechanisms PDF

By Rosaleen Anderson,Paul Groundwater,Adam Todd,Alan Worsley

Antibacterial brokers act opposed to bacterial an infection both via killing the bacterium or via arresting its progress. They do that by way of focusing on bacterial DNA and its linked strategies, attacking bacterial metabolic strategies together with protein synthesis, or interfering with bacterial mobilephone wall synthesis and function.

Antibacterial Agents is a vital advisor to this significant type of chemotherapeutic medicines. Compounds are organised in accordance with their goal, which is helping the reader comprehend the mechanism of motion of those medications and the way resistance can come up. The ebook makes use of an built-in “lab-to-clinic” strategy which covers drug discovery, resource or synthesis, mode of motion, mechanisms of resistance, medical facets (including hyperlinks to present instructions, major drug interactions, cautions and contraindications), prodrugs and destiny improvements.

Agents coated include:

  • agents concentrating on DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents
  • agents concentrating on metabolic tactics -  sulfonamide antibacterial brokers and trimethoprim
  • agents concentrating on protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones
  • agents focusing on mobile wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin

Antibacterial Agents will discover a position at the bookshelves of scholars of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.

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Antibacterial Agents: Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications by Rosaleen Anderson,Paul Groundwater,Adam Todd,Alan Worsley

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